Base Editors Finding Tool

If you use BE-FF, please cite: Roy Rabinowitz, Shiran Abadi, Shiri Almog, Daniel Offen, Prediction of synonymous corrections by the BE-FF computational tool expands the targeting scope of base editing, Nucleic Acids Research, Volume 48, Issue W1, 02 July 2020, Pages W340–W347, https://doi.org/10.1093/nar/gkaa215

Optional: Enter a customized PAM here


Results

Original Ref. Sequence:

Original Var. Sequence:

The following base editors will correct this variance (and no other bases around it):
Base Editor Corrected Sequence PAM
The following base editors will correctly edit the SNP. However it may also edit other flanking nucleotides. Such changes are synonymous substitutions and the resulted amino acid sequence will probably be as good as the reference sequence:
Base Editor Corrected Sequence PAM

** Please note that minor editing may occur